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An Arthritis-Suppressive and Treg Cell–Inducing CD41 T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses
Immunology Review 2017 on tolDC and HSP
Tolerogenic dendritic cells (tolDCs) are a promising therapeutic tool to
restore immune tolerance in autoimmune diseases.
Heat shock proteins and their immunomodulatory role in inflammatory arthritis
Autoimmune diseases, including inflammatory arthritis, are characterized by a loss of self-tolerance, leading to an excessive immune responses and subsequent ongoing inflammation.
Regulatory T cells that recognize a ubiquitous stress-inducible self-antigen are long-lived suppressors of autoimmune arthritis
Heat shock proteins are no DAMPs, rather ‘DAMPERs’
In The Press
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